Body Regulator
نویسندگان
چکیده
منابع مشابه
Identification of RNF168 as a PML nuclear body regulator.
Promyelocytic leukemia (PML) protein forms the basis of PML nuclear bodies (PML NBs), which control many important processes. We have screened an shRNA library targeting ubiquitin pathway proteins for effects on PML NBs, and identified RNF8 and RNF168 DNA-damage response proteins as negative regulators of PML NBs. Additional studies confirmed that depletion of either RNF8 or RNF168 increased th...
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OBJECTIVE The angiopoietin-like protein 4 (Angptl4)/fasting-induced adipose factor (Fiaf) is known as a regulator of peripheral lipid and glucose metabolism. In the present study, we investigated the physiological role of Angptl4 in central regulation of body weight homeostasis. RESEARCH DESIGN AND METHODS Hypothalamic Angptl4 expression levels were measured using immunoblot assay during feed...
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ژورنال
عنوان ژورنال: Nature
سال: 1970
ISSN: 0028-0836,1476-4687
DOI: 10.1038/228093a0